Stanislav A. Grabovskii, Ph.D, MBA

Stanislav A. Grabovskii, Ph.D, MBA

Senior Research Scientist | Biomedical Applications & Tissue Regeneration Expert
Ufa, RU.

About

Highly accomplished Senior Research Scientist with over 27 years of expertise in physical organic chemistry and biomedical applications, including tissue regeneration and lipidomics. Holds a Ph.D. and an MBA, demonstrating a unique blend of deep scientific knowledge and strategic leadership. Proven track record of developing patented bioactive compounds, publishing over 70 peer-reviewed articles, and leading international research teams to advance molecular diagnostics and therapeutic strategies for global health challenges.

Work

Ufa Institute of Chemistry, UFRS, Russian Academy of Science
|

Senior Research Fellow

Ufa, Bashkortostan Republic, Russian Federation

Summary

Led advanced research programs in oxidation chemistry, antioxidants, reaction kinetics, and tissue regeneration, driving innovation in biomedical applications.

Highlights

Supervised multiple PhD students, fostering the next generation of scientific talent and contributing to academic excellence.

Authored over 70 peer-reviewed publications in high-impact journals, significantly advancing the fields of physical organic chemistry and biomedical applications.

Secured substantial research funding and cultivated multiple international collaborations, expanding research scope and impact.

Developed a patented bioactive compound (RU2677327) for nerve, skin, and bone repair, demonstrating preclinical efficacy with a 63.9% reduction in skin damage and 63.2% increase in myelin fiber regeneration.

I.S.O.F., Consiglio Nazionale delle Ricerche
|

Visiting Scientist

Bologna, Emilia-Romagna, Italy

Summary

Collaborated on lipid chemistry and biomolecule oxidation research, developing standards for lipidomic analysis and enhancing molecular diagnostics expertise.

Highlights

Collaborated on critical research in lipid chemistry and biomolecule oxidation, contributing to international scientific advancements.

Developed robust standards for lipidomic analysis (DOI: 10.1021/tx200467c), directly enhancing capabilities in molecular diagnostics.

Engaged in interdisciplinary research, strengthening expertise in applying advanced chemical principles to biomedical challenges.

Ufa Institute of Chemistry, UFRS, Russian Academy of Science
|

Research Fellow

Ufa, Bashkortostan Republic, Russian Federation

Summary

Participated as a principal investigator in studies on organic molecule oxidation and conducted foundational research in lipid chemistry.

Highlights

Served as a principal investigator in studies focusing on the oxidation of organic molecules utilizing ozone and dioxiranes, contributing critical insights to reaction mechanisms.

Conducted foundational studies in lipid chemistry, establishing precise lipid analysis standards (DOI: 10.1021/tx200467c) essential for health diagnostics and personalized medicine.

Contributed to research on the reactivity of uracil derivatives with peroxyl radicals, advancing antioxidant chemistry with potential biomedical applications (DOI: 10.1002/poc.4065).

Institut für Organische und Biomolekulare Chemie, Georg-August-Universität Göttingen
|

Visiting Scientist

Göttingen, Lower Saxony, Germany

Summary

Conducted advanced research on the synthesis and oxidation of highly strained polycyclic compounds, strengthening interdisciplinary research capabilities.

Highlights

Performed cutting-edge research on the synthesis and oxidation of highly strained polycyclic compounds, expanding knowledge in organic chemistry.

Applied advanced organic synthesis techniques to develop compounds with potential biomedical applications, bridging chemistry and medicine.

Enhanced interdisciplinary research capabilities through collaboration in a leading German academic institution.

Ufa State Oil Technical University
|

Senior Lecturer, Chemical Department

Ufa, Bashkortostan Republic, Russian Federation

Summary

Delivered comprehensive lectures and seminars on electrochemistry, physical chemistry, and physicochemical analysis methods to university students.

Highlights

Taught advanced courses in electrochemistry, physical chemistry, and physicochemical analysis, educating future scientists and engineers.

Designed and led engaging seminars, enhancing student understanding of complex chemical principles and analytical techniques.

Mentored students in laboratory settings, guiding them through practical applications of chemical theory and research methodologies.

Education

World-Class Scientific & Education Center of the Republic of Bashkortostan
Ufa, Bashkortostan Republic, Russian Federation

MBA

Science

Institute of Organic Chemistry, Ufa Research Center, Russian Academy of Science & I.S.O.F., Consiglio Nazionale delle Ricerche
Ufa, Bashkortostan Republic, Russian Federation

Ph.D.

Physical Chemistry

Courses

Thesis: "The Contribution of Molecular and Radical Directions in the Oxidation of Organic and Silicon Organic Compounds with Dimethyldioxirane."

Bashkir State University
Ufa, Bashkortostan Republic, Russian Federation

Master of Science

Chemistry

Grade: Diploma with Honors

Awards

Young Candidates of Sciences Award

Awarded By

Charitable Foundation for the Promotion of Russian Science

Awarded for early-career research in physical organic chemistry, specifically focusing on oxidation mechanisms.

Publications

Antioxidant Mechanism of Edaravone and Its Amine Analogs: Combined Kinetic and DFT Study

Published by

Bioorganic Chemistry

Summary

Investigated the antioxidant mechanism of edaravone and its analogs through combined kinetic and DFT studies, contributing to understanding reactive oxygen species.

Regioselectivity Control in the Reaction of Cross-Conjugated Enynones with Monosubstituted Hydrazines: Original Synthesis of Luminescent 5-Styrylpyrazoles with a 1-Benzo[d]thiazole Ring

Published by

The Journal of Organic Chemistry

Summary

Published on regioselectivity control in enynone reactions, presenting an original synthesis of luminescent styrylpyrazoles with potential applications in materials science or diagnostics.

High-Pressure Pathway in the Two-Stage Synthesis of 5-Amino-3-Hydroxy-1-Phenyl-1H-Pyrazole

Published by

Letters in Organic Chemistry

Summary

Explored high-pressure synthetic pathways for novel pyrazole derivatives, showcasing expertise in advanced organic synthesis techniques.

Composition For Stimulation Of Reparative Regeneration Of Epithelial, Nerve And Bone Tissues

Published by

Russian Federation Patent

Summary

Developed a patented composition (RU2677327) with proven efficacy in preclinical models for nerve, skin, and bone repair, demonstrating significant regenerative potential.

Languages

German

Conversational

English

Proficient

Italian

Proficient

Russian

Native

Skills

Research & Development

Oxidation Chemistry, Antioxidant Chemistry, Reaction Kinetics, Tissue Regeneration, Lipidomics, Redox Biology, Molecular Mechanisms, Disease Prevention, Biomedical Applications, Molecular Diagnostics, Interdisciplinary Research, Preclinical Models, Scientific Writing, Peer-Reviewed Publications.

Synthetic Chemistry

Organic Synthesis, High-Pressure Synthesis, Free Radical Chemistry, Polycyclic Compounds, Uracil Derivatives, Enynone Synthesis.

Analytical Techniques

LC-MS, GC-MS, NMR, EPR, IR, Raman, UV-Vis Spectroscopy, Mass Spectrometry, Lipidomic Profiling, Biomarker Discovery, Physicochemical Analysis.

Computational & Data Analysis

Computational Chemistry, Ab Initio, DFT, Kinetic Modeling, Fortran, Pascal, Assembler, Gaussian, Jandel SigmaPlot, Data Interpretation.

Project & Team Leadership

Project Leadership, Team Management (25+ researchers), Research Program Management, Grant Acquisition, International Collaboration, Strategic Planning, Problem Solving, Mentorship.

Software

MS Office, SigmaPlot, MestReNova, Gaussian, ChemOffice, Adobe Photoshop.

References

Prof. Dr. Thanasis Gimisis

gimisis@chem.uoa.gr

Dr. Alexei Khalizov

khalizov@njit.edu

Dr. Qadir Timerghazin

qadir.timerghazin@marquette.edu

Prof. Dr. Ioannis Lykakis

lykakis@chem.auth.gr

Projects

Kinetic, Spectral-Luminescent, and Theoretical Investigation of Key Intermediates in Chemical and Biochemical Oxidation Processes

Summary

Led a major research initiative focused on understanding reactive oxygen species intermediates and their applications in biochemistry, funded by the Russian Ministry of Science and Higher Education.

Reactivity of Molecules Containing Active Oxygen in the Oxidation Processes of Organic Compounds

Summary

Directed studies on oxidation mechanisms of organic compounds containing active oxygen, with direct implications for biomedical applications, funded by the Russian Ministry of Science and Higher Education.

Oxidative Processes Involving Reactive Oxygen Species (Grant AAAA-A20-120012090025-2)

Summary

Served as Principal Investigator for funded research into oxidative processes involving reactive oxygen species, with direct implications for tissue regeneration studies.

Development of Tissue Regeneration Compounds (Russian Science Foundation Grant No. 16-15-00141)

Summary

Principal Investigator for a grant-funded project focused on the development of novel tissue regeneration compounds, culminating in a patent.

Development of Lipidomic Standards for Health Diagnostics (International Collaborative Grant CNR (Italy) – RAS (Russia))

Summary

Principal Investigator in an international collaborative grant to develop lipidomic standards critical for health diagnostics.